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With age, bones lose density and cartilage loses elasticity. For people who want to stay on the move for decades to come.
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Four fronts in one capsule: joints and cartilage, bones, heart and immunity.Four fronts in one capsule: joints and cartilage, bones, heart and immunity. Omega-3 from wild Peruvian anchovies, vitamin D3 4000 IU with K2 MK-7, undenatured type II collagen, vitamin C, tetrahydrocurcuminoids, ginger and boron. Oil phase and pellets sealed together, instead of five separate jars.
EPA 280 mg + DHA 210 mg. EPA and DHA contribute to the normal function of the heart (the beneficial effect is obtained with a daily intake of 250 mg).
D3 4000 IU + K2 MK-7 100 µg. Vitamins D and K contribute to the maintenance of normal bones. Vitamin D contributes to the maintenance of normal muscle function and to the normal function of the immune system.
Vitamin C 200 mg + type II collagen 80 mg. Vitamin C contributes to normal collagen formation for the normal function of cartilage.
90-day money-back guarantee. Two jars last 90 days, the time it takes for your vitamin D level and the omega-3 level in your blood cells to stabilize.
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“I wanted to add something to my routine based on omega-3 fatty acids and vitamins. I started by checking a specific detail:...”
“I like being able to find out about the ingredients in a product. Ginger and boron give me a good starting point...”
“What caught my attention? Type II collagen UC-II. What made me spend longer reading the description? Ginger and boron.”
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Food supplements should not be used as a substitute for a varied diet. For adults only. Contains fish. Before use, it is advisable to have a 25(OH)D blood test and to discuss the result with a doctor or pharmacist. Not suitable for people predisposed to kidney stones. People taking anticoagulants from the vitamin K antagonist group (e.g. warfarin, acenocoumarol) should consult a doctor before use.
Four fronts, one capsule: the musculoskeletal system, the heart and immunity, with one shared mechanism underneath it all: what your body does with calcium.
Vitamins C, D and K support the health of bones, cartilage and muscles. The omega-3 fatty acids EPA and DHA are involved in regulating inflammatory processes, while type II collagen, curcumin and ginger round out the formula with ingredients studied in the context of joint health.
Four areas the formula supportsJoint support for everyday movement.
Vitamin C supports the production of the collagen needed for normal cartilage function. Omega-3 fatty acids are involved in regulating inflammatory processes in tissues.
What does it do for you? You support the joint structures you rely on when walking, climbing stairs and doing squats.
A strong foundation for your fitness.
Vitamin D3 increases the absorption of calcium and phosphorus, and K2 helps maintain normal bones. Omega-3s are involved in metabolic processes that are also being studied in the context of bone health.
What does it do for you? You support the maintenance of normal bones, which carry your body weight and the loads of physical activity every day.
Normal muscle function, every day.
Vitamin D3 helps maintain normal muscle function. Omega-3s are incorporated into muscle cell membranes and influence their properties and signaling processes.
What does it do for you? You support the muscles you need for walking, keeping a stable posture and staying physically active.
Joint support for an active lifestyle.
EPA and DHA are precursors of compounds involved in the natural resolution of inflammation. Curcuminoids and ginger are also being studied for their effect on the inflammatory response.
What does it do for you? In some people, well-chosen omega-3 supplementation may help ease discomfort associated with joint inflammation, supporting comfortable everyday movement.
Vitamin D3 is involved in regulating calcium balance, muscle function and immunity. A deficiency can affect many areas of health, and in men, low vitamin D levels are also sometimes linked to lower testosterone levels.
Key markers worth keeping an eye onAn indicator of your body’s vitamin D status.
An important marker of men’s hormonal health; its link with vitamin D is being researched.
Important for bone health and normal muscle function.
Important for metabolic and cardiovascular health.
What does this mean for you? An adequate intake of vitamin D3 and omega-3 fatty acids supports the normal functioning of your body and helps you look after selected areas of health in the long term.
The omega-3 fatty acids EPA and DHA support the normal function of the heart.
What does it do for you day to day?You support the normal function of your heart, which every day delivers blood, oxygen and nutrients to your whole body.
DHA is an important component of nerve cells and contributes to the maintenance of normal brain function.
What does it do for you day to day?You support your brain, which is responsible for remembering information, concentration, logical thinking and decision-making, both at work and in everyday life.
Vitamin D3 supports the normal function of the immune system and is involved in regulating the immune response.
What does it do for you day to day?You help maintain the normal function of your body’s natural defense mechanisms, especially during periods of limited sun exposure.
DHA is an important component of the retina and contributes to the maintenance of normal vision.
What does it do for you day to day?You support normal vision, which you rely on when reading, working at a computer, driving and going about everyday tasks.
Your skin makes vitamin D when exposed to sunlight. In Poland and at similar latitudes, from October to March there isn’t enough of this sunlight for the skin to produce it, even on a sunny day. During those six months, you can get vitamin D mainly from diet and supplements.
Omega-3, D3, K2, collagen and curcumin in one formula. Whatever your age and pace of life, your body needs the right support. That’s why we combined ingredients that support the health of your bones, muscles, heart, brain and immune system.

With age, bones lose density and cartilage loses elasticity. For people who want to stay on the move for decades to come.

Little sun, lots of responsibilities and not much fish in your diet? Top up key nutrients that support immunity, the heart and normal brain function.

Joints and bones under load. Vitamin C contributes to the normal function of the immune system during and after intense physical exercise.
What can your body gain?
Consistent supplementation helps gradually build up your vitamin D3 and omega-3 levels, supporting immunity, muscles, bones, heart and brain. See what changes may take place in your body.
of vitamin D3 per daily serving, i.e. 100 µg and 2000% of the RI.
It’s worth testing your 25(OH)D level before you start.
Vitamin D3 begins to gradually replenish your levels, supporting the normal function of the immune system and muscles.
What can you gain? If you are deficient in vitamin D, the deficiency starts to be corrected. It’s the first step toward restoring an adequate supply of a nutrient that matters for immunity and muscle function.
Vitamin C supports the natural production of the collagen needed for normal cartilage function. Omega-3s are involved in regulating inflammatory processes, and type II collagen completes the formula.
What can you gain? You support the joint structures you need for walking, climbing stairs and training. Some people may notice changes in how comfortable movement feels, although this is not a confirmed effect of this formula after 30 days.
Vitamin D3 increases the absorption of calcium and phosphorus, and K2 activates proteins involved in bone metabolism. After two months, your blood vitamin D level may already be noticeably higher.
What can you gain? You support the maintenance of normal bones and normal muscle function. If you were previously deficient in D3, correcting the deficiency may matter for your physical fitness.
After 90 days, your blood vitamin D3 level may rise significantly, and more EPA and DHA may be incorporated into your cell membranes, increasing your omega-3 index.
What can you gain? A better supply of nutrients that support your heart, brain, immunity and muscles. Men may also want to monitor their testosterone, as low vitamin D levels are sometimes linked to lower testosterone. However, there is no certainty that D3 supplementation will raise testosterone.
A typical omega-3 capsule is just oil. Here, the oil is a carrier for vitamins D3 and K2, and alongside it, in pellets, five more ingredients get to work.
| What matters | VITAL OMEGA PRO™ | Separate products | Typical omega-3 |
|---|---|---|---|
| EPA + DHA per serving | 490 mg | 1 jar | Depends on the brand |
| Vitamin D3 | 4000 IU | 1 jar | Rarely, or 1000–2000 IU |
| Vitamin K2 as MK-7 | 100 µg | 1 jar | Rarely |
| Undenatured type II collagen | 80 mg | 1 jar | — |
| Vitamin C | 200 mg | 1 jar | — |
| Tetrahydrocurcuminoids, ginger and boron | Yes | 3 jars | — |
| Oil protected with tocopherols and rosemary | Yes | Depends on the brand | Depends on the brand |
| Capsules per day | 2 | 6–10 | 2–3 (omega only) |
Oil phase + pellets
Oil 40% EPA · 30% DHA
With K2 MK-7 100 µg
Test the formula for yourself
This capsule is transparent because it has nothing to hide. Micropellets with five more ingredients float in golden oil with vitamins D3 and K2. Normally, that takes two different technologies and two different products.
Fish oil · D3 · K2
What is it? 700 mg of oil from wild Peruvian anchovies (EPA 280 mg, DHA 210 mg), with vitamins D3 and K2 dissolved in it.
What does it mean? Vitamins D and K are fat-soluble. In one study, vitamin D3 taken with a meal containing fat was absorbed better than when taken without fat.1
Put simply The oil isn’t a filler. It’s transport for the vitamins.
5 ingredients in solid form
What is it? Vitamin C, undenatured type II collagen, tetrahydrocurcuminoids, ginger and boron, sealed in small pellets suspended in the oil.
What does it mean? Solid ingredients and oil usually go into separate capsules because they don’t mix. The pellets keep the solids separate from the oil, so both can share one capsule.
Put simply Five fewer jars, the same serving.
Liquid-fill · sealed
What is it? A hard, transparent shell filled with liquid and tightly sealed so the oil doesn’t leak.
What does it mean? Tocopherols and rosemary oil protect the oil from oxidation, and the sealed capsule limits its contact with air. You can see the oil and pellets through the shell.
Put simply You see what you take.
Illustrative diagram. 1 Dawson-Hughes B. et al., J Acad Nutr Diet 2015;115(2):225-230. The description of digestive physiology concerns fats and fat-soluble vitamins; it is not a claim about the product’s effects.
8 ingredients on four levels: from absorption, through calcium balance and cartilage, to cell membranes.
Vitamins D3 and K2 are fat-soluble. The fish oil in the same capsule is their natural carrier.
D3 increases calcium absorption, and K2 activates osteocalcin, which binds calcium into bone.
Vitamin C stabilizes collagen, and type II collagen is the main protein of articular cartilage.
EPA and DHA are incorporated into cell membranes, and polyphenols act on signaling pathways.
Vitamins and oil · daily serving
% RI: percentage of the reference intake for adults. Values per 2 capsules.
Fish oil 700 mg from wild Peruvian anchovies: EPA 280 mg · DHA 210 mg · other
EU-authorized health claims
EPA and DHA contribute to the normal function of the heart. The beneficial effect is obtained with a daily intake of 250 mg of EPA and DHA.
Vitamin D contributes to normal absorption of calcium and phosphorus, to normal blood calcium levels, and to the maintenance of normal bones and teeth, normal muscle function and the normal function of the immune system.
Vitamin K contributes to the maintenance of normal bones and to normal blood clotting.
Vitamin C contributes to normal collagen formation for the normal function of cartilage, bones and blood vessels, and to the normal function of the immune system, including during and after intense physical exercise.
Vitamin C contributes to the protection of cells from oxidative stress and to the reduction of tiredness and fatigue.
700 mgOil from wild Peruvian anchovies: 40% EPA and 30% DHA. EPA and DHA contribute to the normal function of the heart.
4000 IU + 100 µgVitamin D helps the body absorb calcium, and vitamin K activates proteins that bind it into bone.
80 mgUndenatured type II collagen, the main protein of articular cartilage, studied for oral tolerance.
110 mgAn extract standardized for tetrahydrocurcuminoids, an active metabolite of curcumin.
DER 4:1A rhizome extract (DER 4:1), a source of gingerols and shogaols, which are studied in relation to COX pathways.
200 mgA cofactor of collagen-stabilizing enzymes. Vitamin C contributes to normal collagen formation for cartilage.
Expand an ingredient to see its mechanism and the research behind it.
EPA and DHA are long-chain omega-3 fatty acids that the body makes from plant-based ALA only to a small extent, which is why their main source is oily sea fish. They are incorporated into cell membranes and are precursors of mediators involved in resolving inflammation. EU health claim: EPA and DHA contribute to the normal function of the heart (with a daily intake of 250 mg; one serving provides 490 mg). Tocopherols and rosemary oil protect the oil from oxidation.
Mechanism: Oil from wild Peruvian anchovies: 40% EPA and 30% DHA. EPA and DHA contribute to the normal function of the heart.
A review of the role of DHA in cell membranes, the brain and the retina.
Calder P.C. (2016), Ann Nutr Metab 69(Suppl 1):7-21The omega-3 index, i.e. the share of EPA and DHA in red blood cell membranes, as a marker of omega-3 status.
Harris W.S., von Schacky C. (2004), Prev Med 39(1):212-220Vitamin D3 is made in the skin under UVB exposure, but in Poland and at similar latitudes this synthesis is practically impossible from October to March. EU health claims: vitamin D contributes to normal absorption and utilization of calcium and phosphorus, to normal blood calcium levels, and to the maintenance of normal bones and teeth, normal muscle function and the normal function of the immune system. 100 µg (4000 IU) is the tolerable upper intake level for adults according to EFSA, so it’s worth testing your 25(OH)D before you start.
Mechanism: Vitamin D helps the body absorb calcium, and vitamin K activates proteins that bind it into bone.
A review of the causes and consequences of vitamin D deficiency.
Holick M.F. (2007), N Engl J Med 357(3):266-281Polish guidelines: vitamin D supplementation is recommended for most adults, at least from October to March.
Płudowski P. et al. (2023), Nutrients 15(3):695MK-7 is the form of vitamin K2 with the longest half-life in the blood. It is involved in the carboxylation of vitamin K-dependent proteins: osteocalcin in bone, MGP in soft tissues, and clotting factors. EU health claims: vitamin K contributes to the maintenance of normal bones and to normal blood clotting. The MGP mechanism is well understood, but it has not been proven that K2 supplementation protects blood vessels from calcification.
Mechanism: Activates osteocalcin and MGP. Vitamin K contributes to the maintenance of normal bones.
MK-7 has a half-life of about 3 days and provides more stable blood levels than vitamin K1.
Schurgers L.J. et al. (2007), Blood 109(8):3279-3283In postmenopausal women, 3 years of MK-7 intake were studied for their effect on bone density and strength.
Knapen M.H. et al. (2013), Osteoporos Int 24(9):2499-2507Unlike hydrolyzed collagen, the undenatured form retains its triple-helix structure. It is studied not as a building block but for the mechanism of oral tolerance, i.e. its contact with the lymphoid tissue of the gut. That’s why studies use doses in the tens of milligrams rather than grams.
Mechanism: Undenatured type II collagen, the main protein of articular cartilage, studied for oral tolerance.
In a 180-day randomized, placebo-controlled study, undenatured type II collagen was assessed for knee discomfort and compared with glucosamine and chondroitin.
Lugo J.P. et al. (2016), Nutr J 15:14Curcumin is poorly absorbed and quickly metabolized. One of its main metabolites is tetrahydrocurcumin (THC), which in preclinical studies showed stronger activity than curcumin itself, including on the NF-κB pathway.
Mechanism: An extract standardized for tetrahydrocurcuminoids, an active metabolite of curcumin.
In animal models, the curcumin metabolites tetrahydrocurcumin and octahydrocurcumin inhibited the TAK1-NF-κB pathway more strongly than curcumin.
Zhang Y. et al. (2018), Front Pharmacol 9:1181A comparison of the anti-inflammatory and antioxidant activity of curcumin and its metabolites.
Xie H. et al. (2020), Evid Based Complement Alternat Med 8856135Ginger is a rhizome that has been used in cooking and traditional medicine for thousands of years. Its pungent compounds, gingerols and shogaols, are being studied for their effects on COX enzymes and the inflammatory response. DER 4:1 means that 4 kg of raw material yields 1 kg of extract.
Mechanism: A rhizome extract (DER 4:1), a source of gingerols and shogaols, which are studied in relation to COX pathways.
A meta-analysis of randomized studies on ginger in people with knee and hip joint discomfort.
Bartels E.M. et al. (2015), Osteoarthritis Cartilage 23(1):13-21Vitamin C is essential for the hydroxylation of proline and lysine, without which the collagen triple helix is unstable. EU health claims: contributes to normal collagen formation for the normal function of cartilage, bones and blood vessels, to the normal function of the immune system (including during and after intense physical exercise, at 200 mg per day), to the protection of cells from oxidative stress and to the reduction of tiredness and fatigue.
Mechanism: A cofactor of collagen-stabilizing enzymes. Vitamin C contributes to normal collagen formation for cartilage.
Review: the role of vitamin C in collagen synthesis.
Peterkofsky B. (1991), Am J Clin Nutr 54(6 Suppl):1135S-1140SBoron is found in nuts, dried fruit and avocados, among other foods. It has no established reference intake or authorized health claims, but it is being studied in the context of mineral metabolism and bone health.
Mechanism: A trace element involved in the metabolism of calcium, magnesium and vitamin D.
A review of research on boron: bones, and vitamin D and magnesium metabolism.
Pizzorno L. (2015), Integr Med 14(4):35-48There are no EU-authorized health claims for type II collagen, tetrahydrocurcuminoids, ginger or boron, so we only describe what they are being studied for. The research concerns the ingredients, not the product.
Three mechanisms described in the scientific literature. Click point 01, 02 or 03 to see the diagram. Stay Demanding. Demand more from yourself, from the formula and from the brand.
Calcium from your diet isn’t enough on its own. Your body has to absorb it and then build it in where it’s needed.1-3
Gut Active vitamin D increases the production of proteins that carry calcium across the intestinal lining.
Blood Vitamin D helps maintain normal blood calcium levels, which nerves and muscles, among others, depend on.
Osteocalcin K2 is involved in the carboxylation of osteocalcin. Only active osteocalcin binds calcium into the bone matrix.
MGP K2 also activates MGP, a protein that inhibits the mineralization of soft tissues. It’s a well-understood mechanism, but not proof of vascular protection.
Muscles Muscle cells have VDR receptors, and every muscle contraction depends on calcium.
Educational material, not related to any product. Sources: Holick M.F., N Engl J Med 2007; Mladěnka P. et al., Front Pharmacol 2022; Knapen M.H. et al., Osteoporos Int 2013.
EPA and DHA are incorporated into cell membranes, where they give rise to molecules that help resolve inflammation.4,5
Resolvins, protectins and maresins. Inflammation isn’t just “on”, it’s also “off”. Specialized mediators derived from EPA and DHA take part in actively switching off the inflammatory response.
Membranes EPA and DHA change the composition of cell membranes and, with it, communication between cells.
Arachidonic acid EPA competes with it for COX and LOX enzymes, which changes the profile of the lipid mediators produced.
Resolution Resolvins, protectins and maresins are involved in resolving the inflammatory response.
Illustrative diagram. It does not depict the effects of any product. Sources: Calder P.C., Ann Nutr Metab 2016; Serhan C.N., Nature 2014;510:92-101.
Articular cartilage has no blood vessels, and its main protein is type II collagen.6,7
1 · TYPE II COLLAGEN The main structural protein of articular cartilage, which gives it strength.
2 · VITAMIN C A cofactor of the enzymes that stabilize the collagen triple helix. Without it, collagen is weaker.
3 · UC-II The undenatured form, studied for oral tolerance rather than as a building block.
4 · MOVEMENT Cartilage is nourished by synovial fluid, which movement “pumps” through it. That’s why regular activity is part of the plan.
Educational material, not related to any product. Sources: Peterkofsky B., Am J Clin Nutr 1991; Lugo J.P. et al., Nutr J 2016.
What each ingredient does, what happens in your body as a result, and what that means for you. A green marker indicates an EU-authorized health claim.
Ingredient · mechanism / What happens in the body / What it does
D3 · VDR receptor in immune cells
Regulates immune cell activity and the production of antimicrobial peptides
EU Contributes to the normal function of the immune system
D3 · calcium and phosphorus absorption
Increases the production of calcium-transporting proteins in the gut
EU Contributes to the maintenance of normal bones and teeth
D3 · VDR receptor in muscles
Influences gene expression in muscle cells
EU Contributes to the maintenance of normal muscle function
K2 · osteocalcin carboxylation
Active osteocalcin binds calcium into the bone matrix
EU Contributes to the maintenance of normal bones
K2 · MGP activation
MGP inhibits the mineralization of soft tissues
Well-understood mechanism; vascular protection is not proven
K2 · carboxylase cofactor
Activates vitamin K-dependent clotting proteins
EU Contributes to normal blood clotting
EPA and DHA · incorporation into cell membranes
Change membrane properties and cell communication, including in the heart
EU Contribute to the normal function of the heart
EPA and DHA · SPM precursors
Give rise to resolvins, protectins and maresins
Studied in the context of resolving inflammation
Vitamin C · hydroxylase cofactor
Stabilizes the collagen triple helix
EU Contributes to normal collagen formation for cartilage and bones
UC-II · oral tolerance
Contact with the lymphoid tissue of the gut (Peyer’s patches)
Studied for joint comfort (Lugo et al. 2016)
Tetrahydrocurcuminoids · NF-κB pathway
A curcumin metabolite, stronger than curcumin in preclinical studies
Studied in vitro and in animals (Zhang 2018, Xie 2020)
Ginger · gingerols
Ginger’s pungent compounds, studied in relation to COX pathways
Studied in people with joint discomfort (Bartels et al. 2015)
Boron · mineral metabolism
Involved in calcium, magnesium and vitamin D metabolism
Studied in the context of bone health (Pizzorno 2015)
Tocopherols and rosemary · oil antioxidants
Limit the oxidation of EPA and DHA in the capsule
Fresh oil, a low TOTOX value, less fishy aftertaste
Because these ingredients complement each other. D3 supports immunity and muscles, D3 with K2 supports normal bones, and EPA and DHA support normal heart function. Vitamins D3 and K2 are fat-soluble, so the fish oil in the same capsule is their natural carrier.
Oil phase (3 ingredients) and pellets (5 ingredients) in one capsule. Pellets suspended in golden oil aren’t a visual gimmick; they’re physical proof that we seal the oil and solid phases together, something standard technology can’t do.
VITAL OMEGA PRO isn’t a blend of “something with omega”. It’s a formula built form by form and dose by dose. Purity, bioavailability and consistency are the SYNTHAGEN standard.
Reviews come from our store’s customers. Individual experiences may vary.
I wanted to add something to my routine based on omega-3 fatty acids and vitamins. I started by checking a specific detail: type II collagen UC-II. Another plus is the formula including omega-3 and ingredients for musculoskeletal support. That's the...
I like being able to find out about the ingredients in a product. Ginger and boron give me a good starting point for my own research.
What caught my attention? Type II collagen UC-II. What made me spend longer reading the description? Ginger and boron.
I've looked through plenty of descriptions in this category. The detail that stuck with me most was the fish oil combined with additional ingredients. That's more informative than just saying 'premium complex.'
I usually see plenty of slogans here. What matters more in this case are the specifics: tetrahydrocurcuminoids. I like descriptions like this.
I wanted to add something to my routine based on omega-3 fatty acids and vitamins. I started by checking a specific detail: type II collagen UC-II. Another plus is the formula including omega-3 and ingredients for musculoskeletal support. That's the...
I like being able to find out about the ingredients in a product. Ginger and boron give me a good starting point for my own research.
What caught my attention? Type II collagen UC-II. What made me spend longer reading the description? Ginger and boron.
I've looked through plenty of descriptions in this category. The detail that stuck with me most was the fish oil combined with additional ingredients. That's more informative than just saying 'premium complex.'
I usually see plenty of slogans here. What matters more in this case are the specifics: tetrahydrocurcuminoids. I like descriptions like this.
Creators sharing their experiences with Synthagen.

Gracjan Szostak@szostak_gracjan
Marlena Jarmasz@marlenajarmasz
Krystian Kipiel@trenuj_z_krystianem
Wiktoria Różańska@thoria.fitness
Maciej Szot@czajebaze
Paulina@paulina.j_m
Ilona Kwiecińska@kwiecinskailona
Patryk Chmura@rozchmurz_sie
Patryk Chmura@rozchmurz_sieAt a dose of 4000 IU, it’s worth knowing your baseline vitamin D level. It’s a simple blood test.
Morning and evening, with a meal containing fat.
45 servings per jar. Two jars last 90 days, after which it’s worth repeating the test.
90-day money-back guarantee. Take VITAL OMEGA PRO™ regularly and see how it fits your routine. If it’s not for you, the money-back guarantee has you covered. Returns policy.
Add to cartDidn’t find the answer to your question? Write to us: [email protected]
Buy VITAL OMEGA PROYou can combine VITAL OMEGA PRO™ with other Synthagen products. Always check the ingredients and don’t double up on vitamin D.



Food supplements should not be used as a substitute for a varied diet.
More formulas from Synthagen Laboratories.