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Who it’s for
When is supplementation worth considering?
- You want to support balanced glucose metabolism
- You want to maintain a healthy body weight
- You follow longevity practices
- You feel sleepy after meals
Metabolic · Longevity4.85· 61 reviews
GLUCO AGEPROTECT™
A formula of six active ingredients aimed at supporting blood sugar balance, improving body composition and supporting longevity. Ships in 24h.
Chromium contributes to the maintenance of normal blood glucose levels and to normal macronutrient metabolism.
White mulberry leaf extract provides DNJ, a compound studied for its effect on carbohydrate-digesting enzymes.
Alpha-lipoic acid (ALA) acts as a cofactor of mitochondrial enzymes involved in obtaining energy from nutrients.
2 caps once daily, with your largest meal30 servings per jar, 60 capsules90-day money-back guarantee, risk-free
€149,97€149,97
You save €0,00€49,99 per jar · €1,66 per day
One-time purchase · Secure online payments
- 30 servings2 capsules per day
- 90 days risk-freeMoney-back guarantee
- 6 active ingredientsSee the formula →
“I appreciate the combination of convenience and transparency. What stands out here is 500 mg of berberine HCl, 100 mg of Ceylon...”
★★★★★Veronica K. · Customer review
“I'm curious about one particular ingredient or detail: white mulberry as a source of DNJ. The other aspects of the formula are...”
★★★★★Paul F. · Customer review
“I first focused on one detail: 500 mg of berberine HCl. Then another: 100 mg of Ceylon cinnamon. The information is specific,...”
★★★★★Conrad Z. · Customer review
Shipping: orders processed within 24 hours, delivery cost shown in the cart (shipping policy) · Contact: [email protected]
Food supplements should not be used as a substitute for a varied diet. A balanced diet and a healthy lifestyle are recommended. For adults only. Do not exceed the recommended daily dose.
Three areas. One formula.
Three areas brought together in one formula: stable glucose, efficient metabolism and the science behind inflammation.
01Stable glucose levels
Stable glucose levels are the foundation of metabolic health.
Chromium contributes to the maintenance of normal blood glucose levels.
- Energy throughout the day
Normal glucose levels are important for supplying cells with energy and avoiding sudden energy dips.
- Focus and mental performance
The brain needs adequate glucose availability to function normally.
- Managing energy from meals
Normal regulation of blood glucose is part of efficient carbohydrate metabolism.
- Long-term metabolic health
Keeping blood glucose within the normal range helps limit the risks associated with chronically elevated blood sugar.
02Efficient metabolism
Normal metabolism is the foundation of a well-functioning body.
It is responsible for converting nutrients into energy and using carbohydrates, fats and proteins, as well as for recovery, tissue repair and maintaining energy balance.
Chromium contributes to normal macronutrient metabolism.
1Energy for daily activities
Normal metabolism converts nutrients into the energy your muscles, brain and other organs need to work.
2Efficient use of nutrients from meals
Carbohydrates, proteins and fats are processed and used according to the body’s current needs.
3Managing energy reserves
The body can store surplus energy and draw on it in periods of increased demand. This does not automatically mean a reduction in body fat.
4Normal brain function
Metabolic processes provide neurons with the energy they need to perform their functions, including processing information.
5Recovery and normal muscle function
Metabolism supplies energy for exercise and allows amino acids to be used to rebuild the body’s proteins.
03Inflammatory processes
Regulation of inflammatory processes.
Inflammation in itself isn’t bad. It is a natural defense and repair mechanism. The problem can be when it persists chronically and out of proportion, which is known as inflammaging.
Scientific background- Longevity: health for longer
Chronic low-grade inflammation is one of the processes studied in the context of biological aging.
- Protection and renewal
A normal inflammatory response lets the body react to damage, initiate tissue repair and switch the response off once the job is done.
- Metabolic and cardiovascular health
Chronic activation of inflammatory processes is linked to metabolic disorders and cardiovascular disease.
- Long-term brain performance
Research on neuroinflammation helps explain the mechanisms behind nervous system aging and changes in cognitive function.
Educational content, unrelated to the product’s effects.
References
- Franceschi C., Campisi J., J Gerontol A Biol Sci Med Sci 2014;69(Suppl 1):S4-9
- Coppé J.P. et al., PLoS Biol 2008;6(12):e301
- López-Otín C. et al., Cell 2013;153(6):1194-1217
Different lifestyles. One foundation.
GLUCO AGEPROTECT™ combines six ingredients in high doses: berberine, white mulberry, bitter melon, cinnamon, ALA and chromium, in a single daily serving, with no proprietary blends. We designed the formula to meet the expectations of the most demanding.
Balanced metabolism
For people who want to take a conscious approach to carbohydrate metabolism, normal blood glucose levels and the efficient use of nutrients.
Body composition
For physically active people who want to take conscious care of their physique and normal metabolism.
90 days of support for blood sugar balance.
From carbohydrate metabolism to maintaining normal blood glucose levels.
See which processes the chromium in our formula supports.
200µg
of chromium in every serving. Chromium contributes to the maintenance of normal blood glucose levels and to normal macronutrient metabolism.¹
1. Commission Regulation (EU) No 432/2012, list of permitted health claims.
- Day14
Glucose after meals.
In the first weeks, what is especially interesting is how the ingredients affect the way the body processes carbohydrates after a meal.
White mulberry contains DNJ, a compound that may limit the activity of carbohydrate-digesting enzymes in the gut. Berberine is being studied for its effect on glucose metabolism.
Potential benefit: some people may see smaller blood glucose rises after meals containing carbohydrates. This does not mean that blood sugar will be more stable for every user after 14 days.
- Day30
Carbohydrate metabolism.
Over a few weeks, the effect of supplementation on processes related to glucose utilization can be considered.
Berberine acts on metabolic pathways, including those linked to AMPK. Alpha-lipoic acid is involved in cellular energy conversion, and chromium contributes to normal macronutrient metabolism.
Potential benefit: studies on berberine have observed improvements in selected markers of blood glucose and insulin resistance. For the user, this could mean more favorable carbohydrate metabolism parameters, if such an effect actually occurs.
- Day60
Glucose metabolism.
After several weeks of regular use, you can look not only at blood glucose after a single meal, but also at parameters that reflect glucose metabolism over a longer period.
In clinical studies of berberine, some participants showed lower fasting glucose and improved markers of insulin sensitivity. Chromium contributes to the maintenance of normal blood glucose levels.
Potential benefit: more favorable glucose readings and selected metabolic parameters, especially in people with pre-existing metabolic disturbances.
- Day90
Long-term metabolic support.
A three-month period allows effects to be considered in a broader perspective, including parameters such as fasting glucose, HbA1c and lipid profile.
In berberine studies lasting from several weeks to a few months, some participants showed improvements in selected parameters of glucose and lipid metabolism.
Potential benefit: a more favorable profile of selected metabolic parameters, which can be assessed with lab tests. This does not mean a guaranteed improvement or lasting effects after 90 days. Three months of supplementation with this formula has not been shown to prevent diabetes, improve body composition or provide a lasting improvement in metabolism.
The difference is clear at a glance.
GLUCO AGEPROTECT™ brings six ingredients together in one serving, in a precisely balanced formula, with the dose of each on the label. A typical berberine supplement has one.
| What matters |  GLUCO AGEPROTECT™ | Single-ingredient berberine |
|---|---|---|
| Berberine HCl | 500 mg | Present |
| White mulberry | 200 mg | None |
| Bitter melon | 200 mg | None |
| Ceylon cinnamon | 100 mg | None |
| Alpha-lipoic acid | 100 mg | None |
| Chromium | 200 µg | None |
6
active ingredientsEach with its dose on the label
0
hidden blendsTransparent ingredients. You know what you’re taking.
500%
chromium RI200 µg per daily serving
90
days risk-freeTest the formula for yourself
From the gut to the mitochondria.
Glucose from a meal goes through four stages: gut, blood, cell and mitochondrion. A different ingredient in the formula works at each one.
The journey of glucose through the body.
Digestive enzymesα-glucosidase breaks down carbohydrates
Glucose curveblood level after a meal
AMPKthe cell’s energy sensor
Mitochondrionwhere energy is produced
glucoseformula ingredientsIllustrative diagram, not to scale
Meet the active ingredients.
The six ingredients are studied for their role at different stages of carbohydrate metabolism, from digestion in the gut to glucose use in the cells.
6 active ingredients
Daily serving: 2 capsules
RI: reference intake. The bars show each ingredient’s dose relative to the largest dose in the serving (berberine, 500 mg). The studies concern individual ingredients, not the product. The only authorized health claims for this formula relate to chromium (Commission Regulation (EU) No 432/2012).
500 mgBerberine HCl
An alkaloid from barberry, studied for activating AMPK, the cell’s energy sensor, which regulates the use of glucose and lipids.
200 mgWhite mulberry
A source of DNJ (1-deoxynojirimycin), studied as an inhibitor of α-glucosidase, the enzyme that breaks down carbohydrates in the gut.
200 mgBitter melon
Contains charantin, polypeptide-p and vicine: compounds studied for their role in glucose metabolism.
100 mgCeylon cinnamon
A natural source of polyphenols, including procyanidins, studied in the context of insulin signaling.
100 mgAlpha-lipoic acid
A cofactor of mitochondrial enzyme complexes that convert nutrients into energy.
200 µgChromium
500% RI. Contributes to the maintenance of normal blood glucose levels. EU health claim.
Ingredients backed by research.
Expand an item to see how it works.
Berberine hydrochloride500 mg
Berberine is a natural alkaloid found in plants such as barberry. It is the subject of numerous scientific studies on carbohydrate and lipid metabolism, including glucose, insulin and cholesterol metabolism.
White mulberry leaf extract200 mg
White mulberry (Morus alba) contains natural bioactive compounds, including 1-deoxynojirimycin (DNJ). This compound is being studied for its effect on the enzymes involved in carbohydrate digestion and on processes related to glucose absorption.
Bitter melon fruit extract200 mg
Bitter melon (Momordica charantia) is a plant traditionally used in Asia. Its bioactive compounds are being studied for their potential role in glucose and carbohydrate metabolism.
Ceylon cinnamon extract100 mg
Ceylon cinnamon (Cinnamomum verum) is a natural source of polyphenols. Compounds found in cinnamon are the subject of research on glucose metabolism and processes related to insulin action.
Alpha-lipoic acid (ALA)100 mg
Alpha-lipoic acid is a compound naturally present in the body, involved in energy production in cells. It is being studied for its antioxidant properties and its potential role in glucose metabolism.
Chromium (chromium picolinate)200 µg · 500% RI
Chromium contributes to the maintenance of normal blood glucose levels and to normal macronutrient metabolism, including carbohydrates, proteins and fats. These effects are covered by health claims authorized in the European Union.
Why care about stable blood sugar?
Three mechanisms described in the scientific literature.
01InflammagingInflammation: a silent factor in aging.
With age, chronic background inflammation rises in many people, even without any infection.1-3
02GlycemiaUnstable blood sugar does steady harm.
Repeated glucose spikes after meals put a strain on the body. It’s not just the average that matters, but also the shape of the curve.4
03Vicious circleThe metabolic vicious circle.
Poor nutrition and frequent glucose spikes sustain inflammation, which the literature describes as a risk factor for metabolic dysfunction.5,6
1 · NUTRITION Poor nutrition and frequent glucose spikes after meals.
2 · INFLAMMATION Glucose spikes sustain inflammation in the body.
3 · METABOLISM High levels of inflammation are a risk factor for metabolic dysfunction.
4 · COMPOSITION It also affects body composition and fat storage.
Educational material, not related to any product. Sources: Hotamisligil 1993; Furman 2019.
Why we created GLUCO3 + 3 = ONE FORMULA
BerberineChromiumWhite mulberry
+ Bitter melon+ Cinnamon+ Alpha-lipoic acid
Why we created GLUCO AGEPROTECT™.
Balanced carbohydrate metabolism depends largely on lifestyle: sleep, stress, diet and physical activity. These are the main factors that shape blood glucose levels. GLUCO AGEPROTECT™ complements the diet and lifestyle of people who look after their glucose levels.
The starting point was a classic combination: berberine, chromium and white mulberry. We added bitter melon, cinnamon and alpha-lipoic acid so that, instead of several separate products, you get one formula in one daily serving.
Each of the six ingredients has its own dose on the label, because we expect a formula to be verifiable.
What customers say.
Reviews come from our store’s customers. Individual experiences may vary.
98%4- and 5-star ratings
61reviews from customers
87%5-star ratings
Customer review
Berberine takes center stageI appreciate the combination of convenience and transparency. What stands out here is 500 mg of berberine HCl, 100 mg of Ceylon cinnamon, and the directions for use.
VK
Veronica K.28.10.2026
Customer review
First of all, white mulberryI'm curious about one particular ingredient or detail: white mulberry as a source of DNJ. The other aspects of the formula are described too, and I always read the label warnings.
PF
Paul F.27.10.2026
Customer review
Berberine, without the hypeI first focused on one detail: 500 mg of berberine HCl. Then another: 100 mg of Ceylon cinnamon. The information is specific, making it easy to compare with my own needs.
CZ
Conrad Z.17.10.2026
Customer review
Clear description: alpha-lipoic acidI don't want to buy blindly. I considered this option because the label clearly lists 100 mg of alpha-lipoic acid. I'm interested in supporting healthy carbohydrate metabolism in my daily routine.
GC
Gabriella C.11.10.2026
Customer review
Alpha-lipoic acid caught my attention100 mg of alpha-lipoic acid? That's exactly what drew me to this formula. Nice job with the description.
RG
Robert G.11.10.2026
Customer review
Berberine takes center stageI appreciate the combination of convenience and transparency. What stands out here is 500 mg of berberine HCl, 100 mg of Ceylon cinnamon, and the directions for use.
VK
Veronica K.28.10.2026
Customer review
First of all, white mulberryI'm curious about one particular ingredient or detail: white mulberry as a source of DNJ. The other aspects of the formula are described too, and I always read the label warnings.
PF
Paul F.27.10.2026
Customer review
Berberine, without the hypeI first focused on one detail: 500 mg of berberine HCl. Then another: 100 mg of Ceylon cinnamon. The information is specific, making it easy to compare with my own needs.
CZ
Conrad Z.17.10.2026
Customer review
Clear description: alpha-lipoic acidI don't want to buy blindly. I considered this option because the label clearly lists 100 mg of alpha-lipoic acid. I'm interested in supporting healthy carbohydrate metabolism in my daily routine.
GC
Gabriella C.11.10.2026
Customer review
Alpha-lipoic acid caught my attention100 mg of alpha-lipoic acid? That's exactly what drew me to this formula. Nice job with the description.
RG
Robert G.11.10.2026
User reviews.
Creators sharing their experiences with Synthagen.
Marlena Jarmasz@marlenajarmasz
Gracjan Szostak@szostak_gracjan
Patryk Chmura@rozchmurz_sie
Paulina Idziak@haavven
Damian Powroźnik@damianpowroznik_thaikox
Wiktoria Różańska@thoria.fitness
Wiktoria Różańska@thoria.fitnessMarlena Jarmasz@marlenajarmaszGet started in three steps.
1
Choose your set
1, 3 or 5 jars. The larger the set, the lower the price per jar.
2
Take 2 capsules daily
Once a day, with your largest meal.
3
Come back for your next jar
30 servings per jar. A set of 3 covers 90 days.
90DAYS RISK-FREE
Try it risk-free.
90-day money-back guarantee. Take GLUCO AGEPROTECT™ regularly and see how it fits your routine. If it’s not for you, you’re covered by our money-back guarantee. Return policy.
Add to cartFrequently asked questions.
Didn’t find the answer to your question? Write to us: [email protected]
Buy GLUCO AGEPROTECTHow do I take GLUCO AGEPROTECT™?
The recommended daily serving is 2 capsules once a day, ideally with a meal, with water. Do not exceed the recommended daily dose.
Why with a meal and not on an empty stomach?
That is the label recommendation: 2 capsules with a meal, ideally your largest one. Do not take the product on an empty stomach.
Does GLUCO AGEPROTECT™ have anti-inflammatory effects or support longevity?
We do not attribute such properties to the product. Inflammaging and blood glucose are topics described in the literature, which we cover in the educational section. The only health claims for this formula relate to chromium (maintenance of normal blood glucose levels and normal macronutrient metabolism).
Can I take it together with medication?
If you take antidiabetic, cholesterol-lowering or anticoagulant medication, consult your doctor before using this product. The formula contains extracts whose effects may add to those of medication.
Does GLUCO AGEPROTECT™ replace medication or diet?
No. It is a food supplement. It does not replace medication, a varied diet or a healthy lifestyle.
Can pregnant or breastfeeding women take it?
The product is intended for adults. Pregnant and breastfeeding women should consult a doctor before use. Do not use if you are hypersensitive to any of the ingredients.
What does 500% RI for chromium mean?
RI stands for reference intake. For chromium it is 40 µg, so 200 µg per daily serving is 500% of that value.
Are the capsules vegan, and what allergens do they contain?
The capsule shell is made of hydroxypropyl methylcellulose (HPMC), a plant-based material.
Why matte glass packaging?
Berberine and alpha-lipoic acid are sensitive to light and oxygen. Matte glass limits light, the metal cap keeps oxygen out, and a sachet inside absorbs moisture. Together, they minimize the risk of the active ingredients degrading.
How long can I use the product?
Use as directed, following the recommended daily serving.
Can I combine GLUCO AGEPROTECT™ with other Synthagen products?
Yes, the products form a single line. Always check the ingredients so you don’t exceed the recommended daily intake of the same ingredients.
A set for your needs.
You can combine GLUCO AGEPROTECT™ with other Synthagen products. Always check the ingredients.
1GLUCO AGEPROTECT™
Chromium 200 µgwith berberine 500 mg
Glucose levelschromium: EU health claim
glucose2PURE OXILLIGENCE™
NAC 400 mgcysteine precursor
Glutathione synthesisthe cell’s own antioxidant
glutathione3VITAL OMEGA PRO™
EPA 280 + DHA 210 mgfrom anchovy oil
HeartEU health claim
heartMetabolism and the cellChromium: contributes to the maintenance of normal blood glucose levels.NAC: provides cysteine, which the cell uses to make glutathione. Studied for its role in oxidative balance.EPA and DHA: contribute to the normal function of the heart (with a daily intake of 250 mg).
GLUCO AGEPROTECT™ + PURE OXILLIGENCE™
GLUCO AGEPROTECT™ + PURE OXILLIGENCE™ + VITAL OMEGA PRO™
€99,98€149,97
Sources: Commission Regulation (EU) No 432/2012 (health claims). Brownlee M., Nature 2001;414:813-820 (glucose, oxidative stress and glycation). Sies H., Berndt C., Jones D.P., Annu Rev Biochem 2017;86:715-748 (glutathione and redox balance). Harris W.S., von Schacky C., Prev Med 2004;39(1):212-220 (the omega-3 index). The products have not been shown to treat any disease. Food supplements should not be used as a substitute for a varied diet. If you take medication or have a chronic condition, consult your doctor before use.
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