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    Indications

    Designed for specific intestinal problems

    IBS and functional disorders

    Butyrate affects intestinal motility and the composition of the microbiota. According to research, it is used as an aid in irritable bowel syndrome, indigestion, constipation, flatulence, abdominal pain, and diarrhea.

    Intestinal inflammation

    Butyrate exerts anti-inflammatory effects by inhibiting pro-inflammatory mediators TNF-α, IL-1β, IL-6 and IL-8and modulating mucosal immunity – one of the best documented SCFAs in the context of inflammatory bowel diseases.

    Intestinal barrier and mucosa.

    By nourishing colonocytes and supporting mucus production, butyrate helps maintain the integrity of the intestinal barrier. It is recommended, among other things, as part of a low-fiber diet and for restoring intestinal flora after antibiotic therapy.

    Mechanism of action

    How butyrate supports the digestive system

    Energy source for colonocytes

    Mechanism
    Butyric acid is the main energy substrate of colonocytes – the epithelial cells of the large intestine, which derive a significant part of their energy requirements from it.

    Meaning
    An adequate supply of butyrate supports epithelial regeneration and intestinal barrier integrity.

    Anti-inflammatory effect

    Mechanism
    Butyrate inhibits proinflammatory mediators (TNF-α, IL-1β, IL-6, IL-8) and modulates the immune response of the intestinal mucosa.

    Meaning
    It is one of the best-studied short-chain fatty acids in the context of gastrointestinal inflammation.

    Concentrated dose in micropelletsa

    Dose
    600 mg sodium butyrate / capsule (480 mg butyric acid); daily portion 2 capsules = 1200 mg butyrate / 960 mg butyric acid.

    Form
    Micropellets ensure prolonged release, product stability and no characteristic odor of sodium butyrate.

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    Butyrate - a key metabolite for a healthy gut

    Butyric acid is the main energy source for colonocytes. A diet low in fiber may result in insufficient natural production of this acid in the intestine, which impacts the health of the intestinal barrier.

    PURE BUTYRATE supplements butyrate directly, in a concentrated dose and enteric-coated form.

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    HOW DOES IT WORK

    Why does it just work?

    PURE BUTYRATE delivers butyric acid directly to where it is naturally produced—the intestine. Micropellets protect the active ingredient, eliminate odor, and release it gradually, even further down the digestive tract.

    High dose, pure composition, consistent quality. This is the SYNTHAGEN standard.

    Concentrated dose
    960 mg of butyric acid per daily serving – the level used in gut health research.

    Micropelleting Technology™
    Extended release, better stability and no characteristic butyrate odor.

    Pure composition
    Sodium butyrate in a plant-based HPMC capsule. No unnecessary fillers, NON-GMO, made in Poland.

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    OPINIONES

    ¿Qué dicen nuestros clientes sobre Synthagen?

    How to take PURE BUTYRATE?

    The recommended daily dose is 2 capsules once daily, preferably with a meal and water. Do not exceed the recommended dose. The package contains 60 capsules—enough for a month's treatment.

    Does sodium butyrate have an unpleasant odor?

    Not in this form. Regular sodium butyrate releases a "rancid butter" odor when in contact with moisture. In PURE BUTYRATE, the substance is encapsulated in micropellets, making it virtually tasteless and odorless—convenient for everyday use.

    What is butyric acid and why do I need it?

    Butyric acid (butyrate) is a short-chain fatty acid naturally produced in the intestine from the fermentation of fiber. It is the primary fuel for intestinal epithelial cells and supports the intestinal barrier and mucosa. A diet low in fiber may result in insufficient natural production.

    Can I combine PURE BUTYRATE with a probiotic?

    Yes—it's a truly natural combination. A probiotic (e.g., GUT BALANCE) rebuilds the microbiome, while butyrate nourishes the intestinal cells and strengthens its barrier function. These products can be safely used together.

    Is the product suitable for vegans?

    Yes. The capsule shell is made of plant-based hydroxypropyl methylcellulose (HPMC). The product is also non-GMO.

    How to store the product and who is it not intended for?

    Store in a tightly closed container in a cool, dry place, away from heat and light. This product is for adults; do not use if you are hypersensitive to any of the ingredients. Pregnant and breastfeeding women should consult a doctor before use.

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