Epithalon 10mg + BAC Water – regenerative and anti-aging peptide.
EPITHALON HAS REGENERATIVE AND ANTI-AGING EFFECTS THANKS TO:
- Telomerase activation – lengthens telomeres in cells, protecting DNA from degradation and supporting their longevity.
- Gene expression regulation – modulates the activity of genes involved in DNA repair, metabolism, and inflammatory processes.
- Circadian rhythm normalization – stabilizes melatonin secretion, improving sleep quality and nighttime regeneration.
- Antioxidant activity – reduces oxidative stress, neutralizes free radicals, and protects mitochondria.
- Supporting cellular immunity – supports tissue regeneration, particularly in the nervous and endocrine systems.
💡 The result: slower cell aging, better sleep, greater immunity and overall improved vitality.
EPITHALON PEPTIDE STRUCTURE
- Amino acid sequence: Ala-Glu-Asp-Gly
- Summary formula: C₁₄H₂₂N₄O₉
- Molecular weight: 390,35 g/mol
- Form: lyophilisate (white, hygroscopic), easily soluble in water

BIOLOGICAL RESEARCH AND EFFECTS
Epithalon, telomeres and DNA
Professor Khavinson's research has shown that Epithalon activates the enzyme telomerase, which rebuilds the ends of chromosomes—telomeres.
Lengthened telomeres translate into slower cell aging and greater cell regeneration capacity.
Epithalon and the Nervous System and Sleep
Epithalon supports circadian rhythm balance by increasing natural melatonin production.
It improves sleep quality, concentration, and the ability to adapt to stress. Clinical studies have shown a reduction in fatigue symptoms and improved cognitive function in older adults.
Epithalon and regeneration and immunity
The peptide enhances the activity of the immune system and supports the regeneration of bone marrow and nervous system cells.
It has immunomodulatory properties, helping the body maintain a balance between inflammatory and regenerative responses.
Epithalon and oxidative stress and aging
Epithalon neutralizes free radicals and protects DNA from oxidative damage.
Animal studies have shown it to extend average lifespan by 25–30% while improving physical performance and stress resistance.
Figure 1. In this study, conducted on animal oocytes, Epithalon demonstrated its ability to inhibit cell aging. The image in the control group shows oocyte cells, the next image shows senescent cells, and the image labeled "Epithalon" demonstrates inhibition of cell aging. The cells in the image exposed to the Epithalon peptide were found in the same number, and any damage to them was minimized, demonstrating the peptide's anti-aging potential.
| Feature | Biological effect |
|---|---|
| Telomerase activation | Slowing down cell aging |
| Regulation of the circadian rhythm | Improving the quality of sleep and regeneration |
| Antioxidant effect | DNA and mitochondria protection |
| Immunity support | Better regeneration and cellular immunity |
| Neuroprotective effect | Improved mood and cognitive functions |
Bibliography
- V.Kh Khavinson, Peptides and Ageing. 2002; 3:11-144
- V.Khavinson, M.Razumovsky, S.Trofimova, R.Grigorian, A.Razumovskaya, Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa, 2002; 365-8
- Apostolopoulos V, Bojarska J, Chai TT, et al. A Global Review on Short Peptides: 2.Frontiers and Perspectives. Molecules. 2021;26(2):430. Published 2021 Jan 15. doi:10.3390/molecules26020430
- Adult Treatment Panel III.: Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel of detection, evaluation and treatment of high blood cholesterol in adults. JAMA 2001, 285: 2486-97
- D.Sibarov, R.Kovalenko, V.Malinin, V.Khavinson, Epitalon influences pineal secretion in stress-exposed rats in the daytime. 2002; 23(5-6):452-4
- L.Kozina, Investigation of antihypoxic properties of short peptides. 2008;21(1):61-7
- V.Khavinson, E.Korneva, V.Malinin, E.Rybakina, I.Ivanovich, S,Shanin, Effect of epitalon on interleukin-1beta signal transduction and the reaction of thymocyte blast transformation under stress. 2002; 23(5-6):411-6
- X.Yue, S. Liu, J. Guo, T. Meng, X. Zhang, H. Li, C. Song, Z. Wang, H. Schatten, Epitalon protects against postovulatory aging-related damage of mouse oocytes in vitro. 2022 Apr 15; 14(7): 3191–3202. 10.18632/aging.204007

